An Investigation of Low Dose Hyper-radiosensitivity-Does it have a Role Clinically ?

@inproceedings{Harney2013AnIO,
  title={An Investigation of Low Dose Hyper-radiosensitivity-Does it have a Role Clinically ?},
  author={D. A. Harney},
  year={2013}
}
Laboratory studies have demonstrated that some radioresistant tumours are hypersensitive to low doses of radiotherapy (<1Gy) and characteristically display features of radioresistance at more conventional radiation doses (2Gy per fraction), i.e. there is excess cell kill at doses <1Gy relative to that predicted by the linear quadratic (LQ) model. This phenomenon is called “low dose hyper-radiosensitivity” (LDHRS). The aim of this thesis was to investigate if LDHRS could be demonstrated in… CONTINUE READING