An International Society of Bipolar Disorders task force report: Precursors and prodromes of bipolar disorder

  title={An International Society of Bipolar Disorders task force report: Precursors and prodromes of bipolar disorder},
  author={G. Faedda and R. Baldessarini and C. Marangoni and A. Bechdolf and M. Berk and B. Birmaher and P. Conus and M. DelBello and A. Duffy and M. Hillegers and A. Pfennig and R. Post and M. Preisig and A. Ratheesh and P. Salvatore and M. Tohen and G. V{\'a}zquez and E. Vieta and L. Yatham and E. Youngstrom and A. V. Van Meter and C. Correll},
  journal={Bipolar Disorders},
  pages={720 - 740}
To clarify the clinical features preceding the onset of bipolar disorder (BD) has become a public health priority for the prevention of high morbidity and mortality. BD remains frequently under‐ or misdiagnosed, and under‐ or mistreated, often for years. 
Clinical Risk Constellations for the Development of Bipolar Disorders
The early recognition of psychiatric disorders has been a focus of research in the last decades and has led to improvements in clinical care, especially in the area of early psychosis. LikeExpand
Diagnostic conversion from unipolar depression to bipolar disorder, schizophrenia, or schizoaffective disorder: A nationwide prospective 15‐year register study on 43 495 inpatients
To examine temporal patterns and predictors for diagnostic conversion from unipolar depression (UD) to bipolar disorder (BD), schizophrenia, and schizoaffective disorder (SAD).
Early identification of bipolar disorder among young adults – a 22‐year community birth cohort
A prediction model of individuals who would develop bipolar disorder (BD) using machine learning techniques in a large birth cohort and it is shown that within this cohort, women with high BPD are more likely to develop the condition than women without it. Expand
Predicting the emergence of full-threshold bipolar I, bipolar II and psychotic disorders in young people presenting to early intervention mental health services.
Identifying risk factors for the onset of either BD or PDs in young people presenting to early intervention services is assisted not only by the increased focus on MLE and PLE, but also by recognising the predictive significance of poorer social function, childhood-onset anxiety and mood disorders, and suicide attempts prior to the time of entry to services. Expand
Index Depressive Episode and Antidepressant Exposure Were Associated with Illness Characteristics of Pediatric Bipolar Disorder.
This is the first large-scale nationwide follow-up study in Turkey that indicated prior antidepressant treatments were associated with an earlier onset of mania in youth, particularly in adolescent females. Expand
Risk Calculators in Bipolar Disorder: A Systematic Review
The risk calculators reviewed in this article present good discrimination power for bipolar disorder, although future replication and validation of the models is needed. Expand
Early detection of bipolar disorders and treatment recommendations for help-seeking adolescents and young adults: Findings of the Early Detection and Intervention Center Dresden
Analysis on the phenomenology of different BD at-risk stages suggests that early detection of individuals presenting with suggested risk factors for the development of BD is feasible in help-seeking young people. Expand
Efficacy of cognitive‐behavioral group therapy in patients at risk for serious mental illness presenting with subthreshold bipolar symptoms: Results from a prespecified interim analysis of a multicenter, randomized, controlled study
This work aimed to investigate whether group CBT can improve symptoms and functional deficits in young patients at risk for SMI presenting with subthreshold bipolar symptoms. Expand
Generalizing the Prediction of Bipolar Disorder Onset Across High Risk Populations.
The clinical circumstances under which the assessment of symptoms occurs impacts RC accuracy; focusing on symptoms related to the onset of BPSD improved generalizability. Expand
25 Years of the International Bipolar Collaborative Network (BCN)
The findings provide a road map for a new round of much needed clinical treatment research studies and emphasize the need for the formation of a new network focusing on child and youth onset of mood disorders with a goal to achieve early precision diagnostics for intervention and prevention in attempting to make the course of bipolar illness more benign. Expand


Type and duration of subsyndromal symptoms in youth with bipolar I disorder prior to their first manic episode
The aim of the present study was to systematically evaluate the prodrome to mania in youth and to establish an experimental procedure to evaluate the relationship between prodrome and mania. Expand
Baseline dimensional psychopathology and future mood disorder onset: findings from the Dutch Bipolar Offspring Study
To identify the early signs of mood disorder development, specifically bipolar disorder (BD), in a population at familial risk for BD.
The predictive validity of bipolar at‐risk (prodromal) criteria in help‐seeking adolescents and young adults: a prospective study
A set of ultra‐high‐risk criteria for bipolar disorder [bipolar at‐risk (BAR)] was developed and the predictive validity of the BAR criteria was determined. Expand
Antecedents of manic versus other first psychotic episodes in 263 bipolar I disorder patients
As initial episode type can predict later morbidity in bipolar disorder, we tested the hypothesis that clinical antecedents might predict initial episode types.
Manic–Depressive Illness: Bipolar Disorders and Recurrent Depression (2nd edn)
  • E. Paykel
  • Psychology
  • British Journal of Psychiatry
  • 2008
[⇓][1] ![Figure][2] The first edition of this book appeared in 1990 and it rapidly became the standard work on bipolar disorder. Some of the tables are still very useful as reviews of specificExpand
Findings from bipolar offspring studies: methodology matters
This review compares different methods of ascertainment and assessment, and their impact on study findings in high‐risk studies of bipolar disorder. Expand
Rationale and first results of developing at-risk (prodromal) criteria for bipolar disorder.
If prospective studies confirm the validity of the recently developed bipolar at-risk criteria, then the criteria would have the potential to open up new avenues of research for indicated prevention in BD and might therefore offer opportunities to ameliorate the severity of, or even prevent BD. Expand
Ten‐year updated meta‐analysis of the clinical characteristics of pediatric mania and hypomania
This work aimed to update a 2005 meta analysis of the prevalence of manic symptoms in youth, in order to determine whether the picture of pediatric mania has changed as research on pediatric bipolar disorder has grown. Expand
Differentiation in the preonset phases of schizophrenia and mood disorders: evidence in support of a bipolar mania prodrome.
A lengthy and symptomatic prodrome makes clinical high-risk research a feasible goal for bipolar disorder and the phenotypic overlap with the schizophrenia prodrome necessitates the concurrent study of both illness prodromes. Expand
Early exposure to parental bipolar disorder and risk of mood disorder: the Flourish Canadian prospective offspring cohort study
The aim of this study was to determine the association between the duration, severity and timing of exposure to parental BD in early childhood and subsequent risk of mood disorder. Expand