An Integrated Model of the Transcriptome of HER2-Positive Breast Cancer

@inproceedings{Kalari2013AnIM,
  title={An Integrated Model of the Transcriptome of HER2-Positive Breast Cancer},
  author={Krishna R. Kalari and Brian Necela and Xiaojia Tang and Kevin J. Thompson and Melissa Lau and Jeanette E. Eckel-Passow and Jennifer M. Kachergus and Stephen K Anderson and Zhifu Sun and Saurabh Baheti and Jennifer M. Carr and Tiffany R. Baker and Poulami Barman and Derek C. Radisky and Richard W. Joseph and Sarah A Mclaughlin and High-Seng Chai and Stephan Camille and David Rossell and Yan W. Asmann and E. Aubrey Thompson and Edith A. Perez},
  booktitle={PloS one},
  year={2013}
}
Our goal in these analyses was to use genomic features from a test set of primary breast tumors to build an integrated transcriptome landscape model that makes relevant hypothetical predictions about the biological and/or clinical behavior of HER2-positive breast cancer. We interrogated RNA-Seq data from benign breast lesions, ER+, triple negative, and HER2-positive tumors to identify 685 differentially expressed genes, 102 alternatively spliced genes, and 303 genes that expressed single… CONTINUE READING
Tweets
This paper has been referenced on Twitter 1 time. VIEW TWEETS

Citations

Publications citing this paper.
SHOWING 1-7 OF 7 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 32 REFERENCES

Predictive genomic markers to chemotherapy and adjuvant trastuzumab via whole genome expression DASL profiling in the N9831 adjuvant study

  • EAE-P Perez, KV Ballman, +10 authors MM Reinholz
  • Cancer Res
  • 2012
1 Excerpt

Similar Papers

Loading similar papers…