Effects of anxiolytic treatment on potentiated startle during aversive image anticipation
- Psychology, BiologyHuman psychopharmacology
This study tested the hypothesis that anxiety behaviors during anticipation of negative images are sensitive to anxiolytic treatment, suggesting that image anticipation probes anxiety systems.
Interoception in anxiety and depression
- PsychologyBrain Structure and Function
The connection between increased but noisy afferent interoceptive input, self-referential and belief-based states, and top-down modulation of poorly predictive signals is integrated into a neuroanatomical and processing model for depression and anxiety.
Defense-related emotions in humans
- Psychology, Biology
It may be concluded that anxiety and panic are qualitatively different emotional states, respectively related to the animal defense reactions to potential and proximal threat.
Subchronic SSRI administration reduces insula response during affective anticipation in healthy volunteers.
- Psychology, BiologyThe international journal of neuropsychopharmacology
Reduced insular and ACC activation in healthy controls during anticipation may be integral to the therapeutic efficacy of SSRIs and may provide a mechanistic approach for the use of pharmaco-fMRI in the identification of novel pharmacotherapeutic agents in patient populations.
An Active Inference Approach to Interoceptive Psychopathology.
- PsychologyAnnual review of clinical psychology
How these dysfunctions potentially manifest in mental illness and how interventions aimed at altering interoceptive processing can help the brain create a more realistic model of its internal state are discussed.
Increased anterior insula activity in anxious individuals is linked to diminished perceived control
- Psychology, BiologyTranslational Psychiatry
Results provide evidence that exaggerated insula activation during the threat of unpredictable shock is directly related to low perceived control in anxiety-prone individuals, and perceived control may constitute an important treatment target to modulate insula activity during anxious anticipation in anxious-disordered individuals.
Interoception of breathing and its relationship with anxiety
A common role of insula in feelings, empathy and uncertainty
- PsychologyTrends in Cognitive Sciences
Anticipatory feelings: Neural correlates and linguistic markers
- Psychology, BiologyNeuroscience & Biobehavioral Reviews
Neural correlates of anxiety sensitivity during masked presentation of affective faces
- PsychologyDepression and anxiety
Findings support the hypothesized role of the right anterior insula in the visceral/interoceptive aspects of AS, even in response to masked affective stimuli.
SHOWING 1-10 OF 37 REFERENCES
Increased amygdala and insula activation during emotion processing in anxiety-prone subjects.
- PsychologyThe American journal of psychiatry
Increased amygdala and insula reactivity to certain types of emotional processing is seen in young adults with increased anxiety-related temperamental traits, and this brain emotion-processing profile may be a functional endophenotype for proneness to (certain kinds of) anxiety disorders.
Functional neuroanatomy of aversion and its anticipation
- Psychology, BiologyNeuroImage
Neural correlates of speech anticipatory anxiety in generalized social phobia
- Psychology, BiologyNeuroreport
BOLD-fMRI brain activity while generalized social phobics and healthy controls anticipated making public speeches showed greater subcortical, limbic, and lateral paralimbic activity and less cortical activity in regions important in automatic emotional processing.
A modern learning theory perspective on the etiology of panic disorder.
- PsychologyPsychological review
The authors propose that PD develops because exposure to panic attacks causes the conditioning of anxiety (and sometimes panic) to exteroceptive and interoceptive cues, which begins the individual's spiral into PD.
Conflict monitoring and anterior cingulate cortex: an update
- BiologyTrends in Cognitive Sciences
Neural systems supporting interoceptive awareness
- Psychology, BiologyNature Neuroscience
In right anterior insular/opercular cortex, neural activity predicted subjects' accuracy in the heartbeat detection task and local gray matter volume correlated with both interoceptive accuracy and subjective ratings of visceral awareness.
Effects of citalopram on worry and brain activation in patients with generalized anxiety disorder
- PsychologyPsychiatry Research: Neuroimaging
Neuroimaging Studies of Amygdala Function in Anxiety Disorders
- Psychology, BiologyAnnals of the New York Academy of Sciences
The development of new neuroimaging paradigms for measuring aspects of amygdala function, as well as the function of related brain regions are discussed, and it is concluded that such tools hold great promise for facilitating progress in relevant basic neuroscience aswell as clinical research domains.