An In Vivo Polymicrobial Biofilm Wound Infection Model to Study Interspecies Interactions

@inproceedings{Dalton2011AnIV,
  title={An In Vivo Polymicrobial Biofilm Wound Infection Model to Study Interspecies Interactions},
  author={Trevor Dalton and Scot E. Dowd and Randall D. Wolcott and Yan Sun and Chase Watters and John A. Griswold and Kendra P. Rumbaugh},
  booktitle={PloS one},
  year={2011}
}
Chronic wound infections are typically polymicrobial; however, most in vivo studies have focused on monospecies infections. This project was designed to develop an in vivo, polymicrobial, biofilm-related, infected wound model in order to study multispecies biofilm dynamics and in relation to wound chronicity. Multispecies biofilms consisting of both Gram negative and Gram positive strains, as well as aerobes and anaerobes, were grown in vitro and then transplanted onto the wounds of mice. These… CONTINUE READING
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