An In-Depth Analysis of Patient-Reported Outcomes in Patients With Chronic Hepatitis C Treated With Different Anti-Viral Regimens

@article{Younossi2016AnIA,
  title={An In-Depth Analysis of Patient-Reported Outcomes in Patients With Chronic Hepatitis C Treated With Different Anti-Viral Regimens},
  author={Zobair M Younossi and Maria Stepanova and Linda Gambee Henry and Fatema Nader and Sharon K. Hunt},
  journal={The American Journal of Gastroenterology},
  year={2016},
  volume={111},
  pages={808-816}
}
OBJECTIVES:Interferon- and ribavirin (RBV)-containing regimens negatively impact patients’ experience. The aim of this study was to quantify the impact of different anti-viral regimens for hepatitis C on patients’ work productivity, fatigue, and other patient-reported outcomes (PROs).METHODS:The PRO data from multicenter multinational phase 3 clinical trials of sofosbuvir with and without interferon or RBV were retrospectively used. Treatment regimens were classified as interferon+RBV… CONTINUE READING
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