An Experimental Study of the Pathological Effects of Cigarette Condensate in the Lungs with Special Reference to Carcinogenesis

@article{Blacklock1961AnES,
  title={An Experimental Study of the Pathological Effects of Cigarette Condensate in the Lungs with Special Reference to Carcinogenesis},
  author={John W. S. Blacklock},
  journal={British Journal of Cancer},
  year={1961},
  volume={15},
  pages={745 - 762}
}
IT has been demonstrated (Blacklock, 1957) that malignant tumours can be produced in the lungs of rats with various carcinogens, such as benzopyrene or methylcholanthrene, and in a small number of rats with the condensate from cigarette smoke. In view of the results with the condensate, it was desirable to repeat the experiments in a larger series of animals and in addition to study the histo-pathological changes in the lungs preceding the development of malignant tumours. To ensure that there… CONTINUE READING

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