An Exonuclease III Protection-Based Electrochemical Method for Estrogen Receptor Assay

Abstract

Estrogen receptor (ER), expressed in approximately 80% of primary breast cancer cells, has proven to be a valuable predictive factor of the disease. Herein, by making use of the specific binding of ER to its DNA response elements, we propose an Exonuclease III (Exo III) protection-based electrochemical method for detecting ER proteins. In this assay, the… (More)
DOI: 10.3390/ijms140510298

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