An Excision-Competent and Exogenous Mosaic Transposon Harbors the tetM Gene in Multiple Mycoplasma hominis Lineages.

@article{Calcutt2015AnEA,
  title={An Excision-Competent and Exogenous Mosaic Transposon Harbors the tetM Gene in Multiple Mycoplasma hominis Lineages.},
  author={Michael John Calcutt and Mark F. Foecking},
  journal={Antimicrobial agents and chemotherapy},
  year={2015},
  volume={59 10},
  pages={6665-6}
}
The presence of the tetracycline resistance determinant tetM has been reported for Mycoplasma hominis (1, 2) and association with Tn916 genes established (3). To identify the mobile genetic element harboring this gene, genome analysis of M. hominis Sprott (isolated from a nongonococcal urethritis patient before 1978 [4]) and targeted PCR/amplicon sequencing of M. hominis 1630 (1984, arthritis isolate [5]) were undertaken. These analyses revealed that in both isolates, truncated Tn916 resides… CONTINUE READING
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