An Evolutionary Conserved Region in the vasa 3′UTR Targets RNA Translation to the Germ Cells in the Zebrafish

@article{Knaut2002AnEC,
  title={An Evolutionary Conserved Region in the vasa 3′UTR Targets RNA Translation to the Germ Cells in the Zebrafish},
  author={Holger Knaut and Herbert Steinbeisser and Heinz Schwarz and C N{\"u}sslein-volhard},
  journal={Current Biology},
  year={2002},
  volume={12},
  pages={454-466}
}
BACKGROUND In many animals, germ cells are set aside from somatic cells early during development to give rise to sperm in males and eggs in females. One strategy to achieve this separation is to localize special cytoplasmic granules to the precursors of the germline. In Drosophila, the vasa gene has been shown to encode an essential component of these granules. While Vasa protein is directly targeted to the forming germ cells of Drosophila, Vasa protein expression in the germline of Xenopus and… CONTINUE READING

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