An Evi1-C/EBPβ Complex Controls Peroxisome Proliferator-Activated Receptor γ2 Gene Expression To Initiate White Fat Cell Differentiation

@article{Ishibashi2012AnEC,
  title={An Evi1-C/EBPβ Complex Controls Peroxisome Proliferator-Activated Receptor γ2 Gene Expression To Initiate White Fat Cell Differentiation},
  author={Jeff Ishibashi and Zeynep Firtina and S. Rajakumari and Kathleen H. Wood and Heather M. Conroe and D. Steger and P. Seale},
  journal={Molecular and Cellular Biology},
  year={2012},
  volume={32},
  pages={2289 - 2299}
}
ABSTRACT Fibroblastic preadipocyte cells are recruited to differentiate into new adipocytes during the formation and hyperplastic growth of white adipose tissue. Peroxisome proliferator-activated receptor γ (PPARγ), the master regulator of adipogenesis, is expressed at low levels in preadipocytes, and its levels increase dramatically and rapidly during the differentiation process. However, the mechanisms controlling the dynamic and selective expression of PPARγ in the adipocyte lineage remain… Expand
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