An Evaluation of the Benefits of Simultaneous Acquisition on PET/MR Coregistration in Head/Neck Imaging

  title={An Evaluation of the Benefits of Simultaneous Acquisition on PET/MR Coregistration in Head/Neck Imaging},
  author={Serena Monti and Carlo Cavaliere and Mario Covello and Emanuele Nicolai and Marco Salvatore and Marco Aiello},
  journal={Journal of healthcare engineering},
Coregistration of multimodal diagnostic images is crucial for qualitative and quantitative multiparametric analysis. While retrospective coregistration is computationally intense and could be inaccurate, hybrid PET/MR scanners allow acquiring implicitly coregistered images. Aim of this study is to assess the performance of state-of-the-art coregistration methods applied to PET and MR acquired as single modalities, comparing the results with the implicitly coregistration of a hybrid PET/MR, in… 

Figures and Tables from this paper

PET/MR in Head and Neck Cancer - An Update.
Evidence from several studies suggests that PET/MR overall performs equally well as PET/CT in the staging and restaging of head and neck cancer and in radiation therapy planning, and a more widespread use of this imaging modality outside major hospitals is currently limited.
Automatic Tumor Segmentation With a Convolutional Neural Network in Multiparametric MRI: Influence of Distortion Correction
Geometrical distortion on diffusion-weighted imaging data in patients with head and neck tumor does not significantly impair CNN segmentation performance in use, and the performance was not significantly different.
Mesh-to-raster region-of-interest-based nonrigid registration of multimodal images
A general mesh-to-raster framework to register RoIs in multimodal images and a comprehensive quantitative evaluation in 2-D using ground truth (GT) provided by the simultaneous truth and performance level estimation (STAPLE) method are contributed.
Reconstruction of Positron Emission Tomography Images Using Gaussian Curvature
A reconstruction algorithm to improve the image reconstruction process, using the weighted Gaussian curvature (WGC) as a regularization term to better deal with noise and preserve the original geometry of the image, such as the lesion structure is proposed.
Simultaneous FDG-PET/MRI detects hippocampal subfield metabolic differences in AD/MCI
Significant structural and metabolic changes within the hippocampus that can be sensitively assessed at the subfield level in a small cohort are found and may be more sensitive for detecting pathological changes using PET-MRI in AD compared to global hippocampal assessment.
Advanced Magnetic Resonance Imaging of the Skull Base.
Cutting-edge clinical and emerging research MR techniques for the skull base, including high-resolution, phase-contrast, diffusion, perfusion, vascular, zero echo-time, elastography, spectroscopy, chemical exchange saturation transfer, PET/MR, ultra-high-field, and 3D visualization are summarized.
AI-based applications in hybrid imaging: how to build smart and truly multi-parametric decision models for radiomics
An overview of current challenges and available solutions to translate radiomics into hybrid PET-CT and PET-MRI imaging for a smart and truly multi-parametric decision model is provided.
The use of positron emission tomography/magnetic resonance imaging in dementia: A literature review
The aim of this review is to critically evaluate the literature from 2016 to 2021 using PET/MRI for the investigation of patients with mild cognitive impairment or dementia, and discuss the evidence base for widening its application into clinical practice.


A strategy for multimodal deformable image registration to integrate PET/MR into radiotherapy treatment planning
An accurate and robust multimodal deformable image registration of CT and MR in the HN region can be performed using a B-spline parametrized transform and LMI+ BEP as optimization metric, and biologically individualized RT based on combined PET/MRI in terms of dose painting is possible.
Performance Measurements of the Siemens mMR Integrated Whole-Body PET/MR Scanner
The performance of the Biograph mMR during independent and simultaneous acquisition of PET and morphologic MR data compares favorably with other state-of-the-art PET/CT and PET/MR scanners, indicating that the integration of the PET detectors in the MR scanner and their operation within the magnetic field do not have a perceptible impact on the overall performance.
Automatic segmentation of the prostate in 3D MR images by atlas matching using localized mutual information.
An automatic method for delineating the prostate in three-dimensional magnetic resonance scans is presented, based on nonrigid registration of a set of prelabeled atlas images, and the segmentation quality is especially good at the prostate-rectum interface.
PET-CT image registration in the chest using free-form deformations
An algorithm for three-dimensional positron emission tomography transmission-to-computed tomography registration in the chest is implemented, using mutual information as a similarity criterion, and a rigid body deformation combined with localized cubic B-splines is used to capture this motion.
Feasibility of multimodal deformable registration for head and neck tumor treatment planning.
A multi-modal fusion scheme for the enhancement of PET/MR viewing
Results show that the fusion scheme composed by a wavelet-domain transform and a gamma-blending better depicts useful information of the original modalities and allows to better unveil the MR signal underlying PET signal in fused images in oncological as well as neurological studies.
PET–MR imaging using a tri-modality PET/CT–MR system with a dedicated shuttle in clinical routine
The tri-modality PET/CT–MR system offers comparative studies using the three different imaging modalities in the same patient virtually at the same time, and may help to develop reliable attenuation algorithms at theSame time.
Imaging in head and neck squamous cell carcinoma: the potential role of PET/MRI
This review focuses on the clinical applications of PET/MRI in head and neck squamous cell carcinoma (HNSCC), and discusses current evidence about the use of combined PET/CT and DW MRI, and explains the rationale and principles ofPET/MR image fusion.
Clinical oncologic applications of PET/MRI: a new horizon.
Positron emission tomography/magnetic resonance imaging (PET/MRI) leverages the high soft-tissue contrast and the functional sequences of MR with the molecular information of PET in one single, hybrid imaging technology to provide information about tumor biology and microenvironment.