An Escherichia coli chromosomal ars operon homolog is functional in arsenic detoxification and is conserved in gram-negative bacteria.

@article{Diorio1995AnEC,
  title={An Escherichia coli chromosomal ars operon homolog is functional in arsenic detoxification and is conserved in gram-negative bacteria.},
  author={Caroline Diorio and Jie Cai and J Marmor and Roman Shinder and Michael S. Dubow},
  journal={Journal of bacteriology},
  year={1995},
  volume={177 8},
  pages={2050-6}
}
Arsenic is a known toxic metalloid, whose trivalent and pentavalent ions can inhibit many biochemical processes. Operons which encode arsenic resistance have been found in multicopy plasmids from both gram-positive and gram-negative bacteria. The resistance mechanism is encoded from a single operon which typically consists of an arsenite ion-inducible repressor that regulates expression of an arsenate reductase and inner membrane-associated arsenite export system. Using a lacZ transcriptional… CONTINUE READING
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