An Envelope-Modified Tetravalent Dengue Virus-Like-Particle Vaccine Has Implications for Flavivirus Vaccine Design.

Abstract

Dengue viruses (DENV) infect 50 to 100 million people each year. The spread of DENV-associated infections is one of the most serious public health problems worldwide, as there is no widely available vaccine or specific therapeutic for DENV infections. To address this, we developed a novel tetravalent dengue vaccine by utilizing virus-like particles (VLPs… (More)
DOI: 10.1128/JVI.01181-17

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Cite this paper

@article{Urakami2017AnET, title={An Envelope-Modified Tetravalent Dengue Virus-Like-Particle Vaccine Has Implications for Flavivirus Vaccine Design.}, author={Akane Urakami and Mya Myat Ngwe Tun and Meng Ling Moi and Atsuko Sakurai and Momoko Ishikawa and Sachiko Kuno and Ryuji Ueno and Kouichi Morita and Wataru Akahata}, journal={Journal of virology}, year={2017}, volume={91 23} }