An Endophytic Taxol-Producing Fungus from Taxus media, Cladosporium cladosporioides MD2

@article{Zhang2008AnET,
  title={An Endophytic Taxol-Producing Fungus from Taxus media, Cladosporium cladosporioides MD2},
  author={Peng Zhang and Peng-peng Zhou and Long-jiang Yu},
  journal={Current Microbiology},
  year={2008},
  volume={59},
  pages={227-232}
}
Fermentation processes using taxol-producing fungi other than Taxus spp. may be an alternative way to produce taxol, which is an important antitumor agent used widely in the clinic setting. In this study, a taxol-producing endophytic fungus strain MD2 was isolated from the inner bark of Taxus media. Strain MD2 produced taxol when grown in potato dextrose liquid medium. The fungal taxol—which was analyzed by ultraviolet, high-performance liquid chromatography and mass spectrometry—was shown to… CONTINUE READING
32 Citations
13 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 32 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 13 references

Molecular cloning of a 10-deacetylbaccatin III-10-O-acetyl transferase cDNA from Taxus and functional expression in Escherichia coli

  • K Wakler, R Croteau
  • Proc Natl Acad Sci USA
  • 2000
Highly Influential
8 Excerpts

Isolation of high molecular weight DNA and double - stranded RNAs from fungi [ J ]

  • J Li, G Strobel, R Sidhu, WM Hess, E Ford
  • Can J Bot
  • 1990

Similar Papers

Loading similar papers…