An Electron Spin Resonance Study of DNA Dynamics Using the Slowly Relaxing Local Structure Model

@inproceedings{Liang2000AnES,
  title={An Electron Spin Resonance Study of DNA Dynamics Using the Slowly Relaxing Local Structure Model},
  author={Zhichun Liang and Jack H. Freed and Robert S. Keyes and A. M. Bobst},
  year={2000}
}
A systematic analysis is presented of the ESR spectra from DNA oligomers of a range of sizes, including a polymer, spin-labeled with nitroxide moieties attached by different tethers. The complexity of the DNA dynamics is dealt with by the use of the general slowly relaxing local structure (SRLS) model, wherein the nitroxide moiety is reorienting in a restricted local environment, which itself is relaxing on a longer time scale. The slower motion describes the global tumbling of the DNA lattice… CONTINUE READING