An Electrochemical DNA Microbiosensor Based on Succinimide-Modified Acrylic Microspheres

  title={An Electrochemical DNA Microbiosensor Based on Succinimide-Modified Acrylic Microspheres},
  author={Alizar Ulianas and Yook Heng Lee and Sharina Abu Hanifah and Lingling Tan},
An electrochemical microbiosensor for DNA has been fabricated based on new acrylic microspheres modified with reactive N-acryloxysuccinimide (NAS) functional groups. Hydrophobic poly(n-butylacrylate-N-acryloxysuccinimide) microspheres were synthesized in an emulsion form with a simple one-step photopolymerization technique. Aminated DNA probe was attached to the succinimde functional group of the acrylic microspheres via covalent bonding. The hybridization of the immobilized DNA probe with the… CONTINUE READING


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