An Electrically Modulated Drug Delivery Device. II. Effect of Ionic Strength, Drug Concentration, and Temperature

@article{DEmanuele1992AnEM,
  title={An Electrically Modulated Drug Delivery Device. II. Effect of Ionic Strength, Drug Concentration, and Temperature},
  author={Aj. D'Emanuele and John Nicholas Staniforth},
  journal={Pharmaceutical Research},
  year={1992},
  volume={9},
  pages={215-219}
}
The effects of various physicochemical parameters on the changes in drug delivery rate produced by an electrophoretic current are examined using a model system. It was shown that ionic strength has an inverse relationship with the change in delivery rate produced by a given current. Small changes in pH were measured during electrophoresis experiments which were considered to be insignificant. Drug reservoir concentration selection is critical in the design of an electrophoretic device and is… CONTINUE READING
BETA

From This Paper

Topics from this paper.

Similar Papers

Loading similar papers…