An Efficient and Environmentally Benign Chemical Synthesis of Testolactone

@inproceedings{Zinczuk2003AnEA,
  title={An Efficient and Environmentally Benign Chemical Synthesis of Testolactone},
  author={Ju{\'a}n Zinczuk and Jos{\'e} A. Bacigaluppo and Mar{\'i}a Isabel Colombo and Raquel M. Cravero and Manuel Gonz{\'a}lez-Sierra and Edmundo A. R{\'u}veda},
  year={2003}
}
Testolactone was obtained commercially by microbial transformation of either testosterone or progesterone and also synthetically, albeit in low yield. The only chemical synthesis of 1 so far described in the literature starting from dehydroepiandrosterone (2) is shown in Scheme 1. The strategy followed in this synthetic approach consisted in the initial… CONTINUE READING