An Effective Method for the Construction of Esters Using Cs2CO3 as Oxygen Source.

Abstract

An effective method for the construction of esters from acyl chloride and halohydrocarbon using Cs2CO3 as an oxygen source was achieved for the first time. The methodology has a wide scope of substrates and can be scaled up. The study of a preliminary reaction mechanism demonstrated that the O in the products comes from Cs2CO3 and this esterification… (More)
DOI: 10.1021/acs.orglett.5b02479

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