An Early Passage Human Isolate of Kyasanur Forest Disease Virus Shows Acute Neuropathology in Experimentally Infected CD-1 Mice.

@article{Basu2016AnEP,
  title={An Early Passage Human Isolate of Kyasanur Forest Disease Virus Shows Acute Neuropathology in Experimentally Infected CD-1 Mice.},
  author={Atanu Basu and Pragya D Yadav and Sharda Prasad and Sachin Badole and Dilip Ratan Patil and Rajendra Motilal Kohlapure and D. T. Mourya},
  journal={Vector borne and zoonotic diseases},
  year={2016},
  volume={16 7},
  pages={
          496-8
        }
}
BACKGROUND Kyasanur Forest disease virus (KFDV) is a tick-borne Flavivirus that causes a severe illness in humans. Disease spectrum can vary from subclinical infection to fatal cases with hemorrhagic complications. The pathology of KFDV remains incompletely understood. METHODS This study describes the histopathologic and immunohistochemical findings in experimentally infected infant CD-1 mice with an early passage human KFDV isolate. RESULTS Acute histological changes were primarily seen in… CONTINUE READING
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