An Automated 3D Algorithm for Neo-cortical Thickness Measurement

  title={An Automated 3D Algorithm for Neo-cortical Thickness Measurement},
  author={Siddharth Srivastava and Frederik Maes and Dirk Vandermeulen and Patrick Dupont and Wim Van Paesschen and Paul Suetens},
A new method is presented for fully automated regional quantification of the human neo-cortical thickness from 3-D MR images. The method does not require explicit extraction of the cortical surface, but instead is based on a geodesic distance transform of the binarized 3-D volumetric gray matter map obtained by automated segmentation. Regional cortical thickness distributions are derived by atlas-based partitioning of the brain. Results for 64 normal controls are presented that show very good… CONTINUE READING