An Arabidopsis photolyase mutant is hypersensitive to ultraviolet-B radiation.

  title={An Arabidopsis photolyase mutant is hypersensitive to ultraviolet-B radiation.},
  author={Laurie G. Landry and Ann E. Stapleton and Jun Ren Lim and Peter Hoffman and John B. Hays and Virginia Walbot and Robert L. Last},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={94 1},
Photolyases are DNA repair enzymes that use energy from blue light to repair pyrimidine dimers. We report the isolation of an Arabidopsis thaliana mutant (uvr2-1) that is defective in photorepair of cyclobutylpyrimidine dimers (CPDs). Whereas uvr2-1 is indistinguishable from wild type in the absence of UV light, low UV-B levels inhibit growth and cause leaf necrosis. uvr2-1 is more sensitive to UV-B than wild type when placed under white light after UV-B treatment. In contrast, recovery in… CONTINUE READING
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