An Arabidopsis mutant impaired in coenzyme A biosynthesis is sugar dependent for seedling establishment.

@article{Rubio2006AnAM,
  title={An Arabidopsis mutant impaired in coenzyme A biosynthesis is sugar dependent for seedling establishment.},
  author={Silvia Rubio and Tony R Larson and Miguel Gonzalez-Guzman and Santiago Alejandro and Ian A Graham and Ram{\'o}n Serrano and Pedro L Rodriguez},
  journal={Plant physiology},
  year={2006},
  volume={140 3},
  pages={830-43}
}
Once the plant coenzyme A (CoA) biosynthetic pathway has been elucidated by comparative genomics, it is feasible to analyze the physiological relevance of CoA biosynthesis in plant life. To this end, we have identified and characterized Arabidopsis (Arabidopsis thaliana) T-DNA knockout mutants of two CoA biosynthetic genes, HAL3A and HAL3B. The HAL3A gene encodes a 4'-phosphopantothenoyl-cysteine decarboxilase that generates 4'-phosphopantetheine. A second gene, HAL3B, whose gene product is 86… CONTINUE READING

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