An Arabidopsis Rhomboid homolog is an intramembrane protease in plants.

@article{Kanaoka2005AnAR,
  title={An Arabidopsis Rhomboid homolog is an intramembrane protease in plants.},
  author={Masahiro M. Kanaoka and Sini{\vs}a Urban and Matthew Freeman and Kiyotaka Okada},
  journal={FEBS letters},
  year={2005},
  volume={579 25},
  pages={5723-8}
}
Regulated intramembrane proteolysis (RIP) is a fundamental mechanism for controlling a wide range of cellular functions. The Drosophila protein Rhomboid-1 (Rho-1) is an intramembrane serine protease that cleaves epidermal growth factor receptor (EGFR) ligands to release active growth factors. Despite differences in the primary structure of Rhomboid proteins, the proteolytic activity and substrate specificity of these enzymes has been conserved in diverse organisms. Here, we show that an… CONTINUE READING