An Anopheles transgenic sexing strain for vector control

@article{Catteruccia2005AnAT,
  title={An Anopheles transgenic sexing strain for vector control},
  author={Flaminia Catteruccia and Jason P Benton and Andrea Crisanti},
  journal={Nature Biotechnology},
  year={2005},
  volume={23},
  pages={1414-1417}
}
Genetic manipulation of mosquito species that serve as vectors for human malaria is a prerequisite to the implementation of gene transfer technologies for the control of vector-borne diseases. Here we report on the development of transgenic sexing lines for the mosquito Anopheles stephensi, the principal vector of human malaria in Asia. Male mosquitoes, expressing enhanced green fluorescent protein (EGFP) under the control of the β2-tubulin promoter, are identified by their fluorescent gonads… CONTINUE READING
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