• Corpus ID: 83253538

An Analysis of Glycolytic Enzymes in the Cellular Response to Metal Toxicity

@inproceedings{Shanmuganathan2009AnAO,
  title={An Analysis of Glycolytic Enzymes in the Cellular Response to Metal Toxicity},
  author={Anupama Shanmuganathan},
  year={2009}
}
Metal toxicity is implicated in neurotoxicity, nephrotoxicity, aging and cancer. Protein oxidation resulting from oxidative stress is now known to be involved in metal toxicity. However, proteomic responses to metal induced oxidative stress have not been characterized. By using the yeast as a model, we characterized these changes occurring in response to sub-lethal doses of metals. Several proteins involved in protein synthesis, ribosome assembly decreased while antioxidant defenses, proteins… 

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