An Alba-domain protein contributes to the stage-regulated stability of amastin transcripts in Leishmania.


Leishmania infantum promastigotes differentiate into amastigote forms within the phagolysosome of mammalian macrophages causing visceral leishmaniasis. Delta-amastins belong to a multigenic surface protein family of potential virulence factors that are specifically expressed in the amastigote life cycle stage through distinct regulatory elements in the 3… (More)
DOI: 10.1111/mmi.12478