An Age-of-Allele Test of Neutrality for Transposable Element Insertions

@article{Blumenstiel2013AnAT,
  title={An Age-of-Allele Test of Neutrality for Transposable Element Insertions},
  author={J. Blumenstiel and X. Chen and M. He and C. Bergman},
  journal={Genetics},
  year={2013},
  volume={196},
  pages={523 - 538}
}
  • J. Blumenstiel, X. Chen, +1 author C. Bergman
  • Published 2013
  • Biology, Medicine
  • Genetics
  • How natural selection acts to limit the proliferation of transposable elements (TEs) in genomes has been of interest to evolutionary biologists for many years. To describe TE dynamics in populations, previous studies have used models of transposition–selection equilibrium that assume a constant rate of transposition. However, since TE invasions are known to happen in bursts through time, this assumption may not be reasonable. Here we propose a test of neutrality for TE insertions that does not… CONTINUE READING
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