An African HIV-1 sequence from 1959 and implications for the origin of the epidemic

  title={An African HIV-1 sequence from 1959 and implications for the origin of the epidemic},
  author={Tuofu Zhu and Bette T Korber and Andre Joseph Nahmias and Edward Hooper and Paul M Sharp and David D. Ho},
There is considerable genetic diversity among viruses of different subtypes (designated A to J) in the major group of human immunodeficiency virus type 1 (HIV-1), the form of HIV that is dominant in the global epidemic. If available, HIV-1 sequences pre-dating the recognition of AIDS could be crucial in defining the time of origin and the subsequent evolution of these viruses in humans. The oldest known case of HIV-1 infection was reported to be that of a sailor from Manchester who died of an… CONTINUE READING
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