An ATP-stimulated factor that enhances the nuclear binding of "activated" receptor-glucocorticoid complex.

@article{Okamoto1984AnAF,
  title={An ATP-stimulated factor that enhances the nuclear binding of "activated" receptor-glucocorticoid complex.},
  author={Kazuki Okamoto and Fumihide Isohashi and Masahisa Horiuchi and Yoichi Sakamoto},
  journal={Biochemical and biophysical research communications},
  year={1984},
  volume={121 3},
  pages={940-5}
}
A macromolecular material that enhances the translocation, or binding, of already "activated" receptor-glucocorticoid complex to nuclei in the presence of 5 mM ATP was separated from the cytosol of rat liver by DEAE-cellulose column chromatography with about 0.025 M NaCl. The molecular weight of the material was about 93,000 +/- 4,900, as determined by agarose gel filtration. After incubation at 60 degrees C for 15 min, this material still had activity to increase the nuclear binding, but on… CONTINUE READING