An ARC/Mediator subunit required for SREBP control of cholesterol and lipid homeostasis

@article{Yang2006AnAS,
  title={An ARC/Mediator subunit required for SREBP control of cholesterol and lipid homeostasis},
  author={Fajun Yang and Bryan W. Vought and John S. Satterlee and Amy Karol Walker and Z. J. Sun and Jennifer L Watts and Rosalie S. deBeaumont and Richard Mako Saito and Sven Hyberts and Shaosong Yang and Christine P. Macol and Lakshmanan Iyer and Robert Tjian and S. A. F. A. van den Heuvel and Anne C Hart and Gerhard Wagner and Anders M. N{\"a}{\"a}r},
  journal={Nature},
  year={2006},
  volume={442},
  pages={700-704}
}
The sterol regulatory element binding protein (SREBP) family of transcription activators are critical regulators of cholesterol and fatty acid homeostasis. We previously demonstrated that human SREBPs bind the CREB-binding protein (CBP)/p300 acetyltransferase KIX domain and recruit activator-recruited co-factor (ARC)/Mediator co-activator complexes through… CONTINUE READING