An ADAM metalloprotease is a Cry3Aa Bacillus thuringiensis toxin receptor.

  title={An ADAM metalloprotease is a Cry3Aa Bacillus thuringiensis toxin receptor.},
  author={Camila Ochoa-Campuzano and Mar{\'i}a Dolores Real and Amparo C. Mart{\'i}nez-Ram{\'i}rez and Alejandra Bravo and Carolina Rausell},
  journal={Biochemical and biophysical research communications},
  volume={362 2},
Bacillus thuringiensis insecticidal proteins toxic action relies on the interaction with receptor molecules on insect midgut target cells. Here, we describe an ADAM metalloprotease as a novel type of B. thuringiensis toxin receptor on the basis of the following data: (i) by ligand blot and N-terminal analysis, we detected a Colorado potato beetle Cry3Aa toxin binding molecule that shares homology with an ADAM10 metalloprotease; (ii) Colorado potato beetle brush border membrane vesicles display… CONTINUE READING


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