Amyotrophic lateral sclerosis

@article{Wijesekera2009AmyotrophicLS,
  title={Amyotrophic lateral sclerosis},
  author={Lokesh C. Wijesekera and Peter Nigel Leigh},
  journal={Orphanet Journal of Rare Diseases},
  year={2009},
  volume={4},
  pages={3 - 3}
}
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterised by progressive muscular paralysis reflecting degeneration of motor neurones in the primary motor cortex, corticospinal tracts, brainstem and spinal cord. Incidence (average 1.89 per 100,000/year) and prevalence (average 5.2 per 100,000) are relatively uniform in Western countries, although foci of higher frequency occur in the Western Pacific. The mean age of onset for sporadic ALS is about 60 years. Overall, there… CONTINUE READING
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