Amyotrophic lateral sclerosis: what role does environment play?

  title={Amyotrophic lateral sclerosis: what role does environment play?},
  author={Aiesha Ahmed and Matthew Paul Wicklund},
  journal={Neurologic clinics},
  volume={29 3},
The cause of sporadic amyotrophic lateral sclerosis (ALS) is not known. Studies associate toxic, dietary, infectious, neoplastic, and physical factors as underlying, predisposing, or pathogenic influences. Historical, conventional, and novel disease mechanisms, acting solely or in concert, convert previously healthy individuals into terminally ill patients. Despite intensive investigations in the previous decades, the underlying cause and effective treatments elude researchers. Discovering… CONTINUE READING

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