Amyotrophic lateral sclerosis: Early contributions of Jean‐Martin Charcot
@article{Goetz2000AmyotrophicLS, title={Amyotrophic lateral sclerosis: Early contributions of Jean‐Martin Charcot}, author={Christopher G. Goetz}, journal={Muscle \& Nerve}, year={2000}, volume={23} }
Amyotrophic lateral sclerosis is historically an important entity because its manifestations involve distinct signs that can be correlated with gray and white matter lesions at specific sites within the central nervous system. Working at the end of the nineteenth century, the celebrated neurologist, Jean‐Martin Charcot, used this disorder as a prototypic example of the power of his research method, termed “méthode anatomoclinique.” Using clinical cases and autopsy material, he showed how…
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