Amyotrophic Lateral Sclerosis Genetic Studies

@article{He2015AmyotrophicLS,
  title={Amyotrophic Lateral Sclerosis Genetic Studies},
  author={Ji He and Marie Mangelsdorf and Dongsheng Fan and Perry F. Bartlett and Matthew A. Brown},
  journal={The Neuroscientist},
  year={2015},
  volume={21},
  pages={599 - 615}
}
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease of obscure etiology. Multiple genetic studies have been conducted to advance our understanding of the disease, employing a variety of techniques such as linkage mapping in families, to genome-wide association studies and sequencing based approaches such as whole exome sequencing and whole genome sequencing and a few epigenetic analyses. While major progress has been made, the majority of the genetic variation involved in ALS is… 

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