Amyloidosis and neurodegeneration result in distinct structural connectivity patterns in mild cognitive impairment.

Abstract

Alzheimer's disease (AD) is increasingly considered as a disconnection syndrome. Previous studies of the structural connectome in early AD stages have focused on mild cognitive impaired subjects (MCI), considering them as a homogeneous group. We studied 168 subjects from the Alzheimer's Disease Neuroimaging Initiative database (116 MCI and 52 cognitively… (More)
DOI: 10.1016/j.neurobiolaging.2017.03.023

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