Amyloidosis (AL). Clinical and laboratory features in 229 cases.

  title={Amyloidosis (AL). Clinical and laboratory features in 229 cases.},
  author={Robert A Kyle and Philip R. Greipp},
  journal={Mayo Clinic proceedings},
  volume={58 10},
At the Mayo Clinic from 1970 to 1980, 229 patients with primary systemic amyloidosis (AL) were examined. Nephrotic syndrome, congestive heart failure, orthostatic hypotension, carpal tunnel syndrome, and peripheral neuropathy were often associated features. Electrophoresis of the serum revealed a spike in only 40%, but immunoelectrophoresis disclosed a monoclonal protein in 68%. Eighty-nine percent of patients in whom it was sought had a monoclonal protein in the serum or urine. The diagnosis… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 158 extracted citations

Surgical Diseases of the Spleen

Trunkey M. Wakim
Springer Berlin Heidelberg • 1997
View 6 Excerpts
Highly Influenced

Response of Bortezomib Chemotherapy in Hepatic Amyloidosis

Journal of investigative medicine high impact case reports • 2018
View 1 Excerpt

A painful diagnosis.

Internal and emergency medicine • 2017
View 1 Excerpt

Similar Papers

Loading similar papers…