Amyloid localized to tenosynovium at carpal tunnel release. Immunohistochemical identification of amyloid type.

@article{Kyle1992AmyloidLT,
  title={Amyloid localized to tenosynovium at carpal tunnel release. Immunohistochemical identification of amyloid type.},
  author={Robert A Kyle and Morie A Gertz and Reinhold Paul Linke},
  journal={American journal of clinical pathology},
  year={1992},
  volume={97 2},
  pages={250-3}
}
Thirty-five patients seen at the Mayo Clinic from 1968 to 1977 who had carpal tunnel syndrome and local deposition of amyloid without evidence of systemic amyloidosis were identified. The unlabeled immunoperoxidase method was used with antisera against purified amyloid proteins of the AA, A kappa, A lambda, AF/ASC1 (prealbumin) (transthyretin), and AB (beta 2-microglobulin) types. In 33 of the 35 patients, amyloid stained with antisera to transthyretin; in the remaining 2 patients, the amyloid… CONTINUE READING