Amyloid load in Parkinson's disease dementia and Lewy body dementia measured with [11C]PIB positron emission tomography.

@article{Edison2008AmyloidLI,
  title={Amyloid load in Parkinson's disease dementia and Lewy body dementia measured with [11C]PIB positron emission tomography.},
  author={Paul Edison and Christopher C. Rowe and Juha O. Rinne and Shikha Ng and Isma{\"i}l Ahmed and Nina M. Kemppainen and Victor Villemagne and Graeme O'Keefe and Kjell N{\aa}gren and Koel Chaudhury and Colin L. Masters and David J. Brooks},
  journal={Journal of neurology, neurosurgery, and psychiatry},
  year={2008},
  volume={79 12},
  pages={1331-8}
}
BACKGROUND Neuropathological studies have reported varying amounts of amyloid pathology in dementia with Lewy bodies (DLB) and Parkinson's disease dementia (PDD). [11C]PIB positron emission tomography (PET) is a marker of brain amyloid deposition. The aim of this study was to quantify in vivo amyloid load in DLB and PDD compared with control subjects and subjects with Parkinson's disease (PD) without dementia. METHODS 13 DLB, 12 PDD, 10 PD subjects and 41 age matched controls (55-82 years… CONTINUE READING
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