Amyloid-like ribbons of amelogenins in enamel mineralization

  title={Amyloid-like ribbons of amelogenins in enamel mineralization},
  author={Karina M. M. Carneiro and Halei Zhai and Li Zhu and Jeremy A. Horst and Melody Sitlin and Mychi Nguyen and Martin Wagner and Cheryl Simpliciano and Melissa Milder and Chun-Long Chen and Paul E Ashby and Johan Svensson Bonde and Wu Li and Stefan Habelitz},
  booktitle={Scientific reports},
Enamel, the outermost layer of teeth, is an acellular mineralized tissue that cannot regenerate; the mature tissue is composed of high aspect ratio apatite nanocrystals organized into rods and inter-rod regions. Amelogenin constitutes 90% of the protein matrix in developing enamel and plays a central role in guiding the hierarchical organization of apatite crystals observed in mature enamel. To date, a convincing link between amelogenin supramolecular structures and mature enamel has yet to be… CONTINUE READING
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