Amyloid-beta is found in drusen from some age-related macular degeneration retinas, but not in drusen from normal retinas.

@article{Dentchev2003AmyloidbetaIF,
  title={Amyloid-beta is found in drusen from some age-related macular degeneration retinas, but not in drusen from normal retinas.},
  author={Tzvete Dentchev and Ann H. Milam and Virginia M-Y Lee and John Q. Trojanowski and Joshua L. Dunaief},
  journal={Molecular vision},
  year={2003},
  volume={9},
  pages={184-90}
}
PURPOSE Age-related macular degeneration (AMD) is the most common cause of irreversible vision loss in the elderly. Increased understanding of the pathogenesis is necessary. Amyloid-beta (Abeta), a major extracellular deposit in Alzheimer's disease plaques, has recently been found in drusen, the hallmark extracellular deposit in AMD. The goal of this study was to characterize the distribution and frequency of Abeta deposits in drusen from AMD and normal post mortem human retinas to gain… CONTINUE READING

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