Amyloid Precursor Protein : Cellular Studies and Animal Models

@inproceedings{Nilsson2006AmyloidPP,
  title={Amyloid Precursor Protein : Cellular Studies and Animal Models},
  author={Tatjana Nilsson},
  year={2006}
}
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterised by a number of neuropathological features, including extracellular deposits composed primarily of amyloid-β (Aβ) peptides. Aβ is derived from proteolysis of the amyloid precursor protein (APP) by consecutive action of βand γ-secretases. APP is a ubiquitously expressed type I… CONTINUE READING