Amyloid-β precursor protein promotes cell proliferation and motility of advanced breast cancer

@inproceedings{Lim2014AmyloidPP,
  title={Amyloid-β precursor protein promotes cell proliferation and motility of advanced breast cancer},
  author={Seunghwan Lim and Byoung Kwon Yoo and Hae-Suk Kim and Hannah Leah Gilmore and Yonghun Lee and Hyun-pil Lee and Seong-Jin Kim and John James Letterio and Hyoung-Gon Lee},
  booktitle={BMC Cancer},
  year={2014}
}
BackgroundAmyloid-β precursor protein (APP) is a highly conserved single transmembrane protein that has been linked to Alzheimer disease. Recently, the increased expression of APP in multiple types of cancers has been reported where it has significant correlation with the cancer cell proliferation. However, the function of APP in the pathogenesis of breast cancer has not previously been determined. In this study, we studied the pathological role of APP in breast cancer and revealed its… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 18 CITATIONS

Amyloid precursor protein and amyloid precursor-like protein 2 in cancer

  • Oncotarget
  • 2016
VIEW 19 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Amyloid precursor protein is overexpressed in bladder cancer and contributes to the malignant bladder cancer cell behaviors.

  • International journal of urology : official journal of the Japanese Urological Association
  • 2018

Cancer and dementia: Two sides of the same coin?

  • European journal of clinical investigation
  • 2018
VIEW 1 EXCERPT
CITES BACKGROUND

References

Publications referenced by this paper.
SHOWING 1-10 OF 52 REFERENCES

Adjuvant treatments for triple-negative breast cancers.

  • Annals of oncology : official journal of the European Society for Medical Oncology
  • 2012
VIEW 1 EXCERPT

Similar Papers

Loading similar papers…