Amyloid-β and tau pathology of Alzheimer's disease induced by diabetes in a rabbit animal model.

@article{Bitel2012AmyloidAT,
  title={Amyloid-β and tau pathology of Alzheimer's disease induced by diabetes in a rabbit animal model.},
  author={Claudine L. Bitel and Chinnaswamy Kasinathan and Rajesh H Kaswala and William L. Klein and Peter H. Frederikse},
  journal={Journal of Alzheimer's disease : JAD},
  year={2012},
  volume={32 2},
  pages={291-305}
}
Alzheimer's disease (AD) is the major age-dependent disease of the brain, but what instigates late-onset AD is not yet clear. Epidemiological, animal model, and cell biology findings suggest links between AD and diabetes. Although AD pathology is accelerated by diabetes in mice engineered to accumulate human-sequence amyloid-β (Aβ) peptides, they do not… CONTINUE READING