Amylin found in amyloid deposits in human type 2 diabetes mellitus may be a hormone that regulates glycogen metabolism in skeletal muscle.

@article{Cooper1988AmylinFI,
  title={Amylin found in amyloid deposits in human type 2 diabetes mellitus may be a hormone that regulates glycogen metabolism in skeletal muscle.},
  author={Garth J S Cooper and Brendan Leighton and George Dimitriadis and Mark Parry-Billings and J. Kowalchuk and Kevin Howland and Jonathan B. Rothbard and Antony C. Willis and Kenneth B. M. Reid},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1988},
  volume={85 20},
  pages={
          7763-6
        }
}
Diabetes-associated peptide has recently been isolated and characterized from the amyloid of the islets of Langerhans in type 2 (non-insulin-dependent) diabetics, and immunoreactivity with antibodies to the peptide has been demonstrated in islet B cells of both normal and type 2 diabetic subjects. In view of the evidence presented in this paper that this 37-amino acid peptide may be a hormone present in normal individuals, we now propose the name "amylin" to replace "diabetes-associated peptide… CONTINUE READING
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