Amylin at the interface between metabolic and neurodegenerative disorders

@inproceedings{Lutz2015AmylinAT,
  title={Amylin at the interface between metabolic and neurodegenerative disorders},
  author={Thomas A Lutz and Urs Meyer},
  booktitle={Front. Neurosci.},
  year={2015}
}
The pancreatic peptide amylin is best known for its role as a satiation hormone in the control of food intake and as the major component of islet amyloid deposits in the pancreatic islets of patients with type 2 diabetes mellitus (T2DM). Epidemiological studies have established a clear association between metabolic and neurodegenerative disorders in general, and between T2DM and Alzheimer's disease (AD) in particular. Here, we discuss that amylin may be an important player acting at the… CONTINUE READING
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Islet amyloid

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  • 2011
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