Amylin: Pharmacology, Physiology, and Clinical Potential.

  title={Amylin: Pharmacology, Physiology, and Clinical Potential.},
  author={Debbie L Hay and Steve Shihong Chen and Thomas A Lutz and David G. Parkes and Jonathan David Roth},
  journal={Pharmacological reviews},
  volume={67 3},
Amylin is a pancreatic β-cell hormone that produces effects in several different organ systems. Here, we review the literature in rodents and in humans on amylin research since its discovery as a hormone about 25 years ago. Amylin is a 37-amino-acid peptide that activates its specific receptors, which are multisubunit G protein-coupled receptors resulting from the coexpression of a core receptor protein with receptor activity-modifying proteins, resulting in multiple receptor subtypes. Amylin's… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 3 times over the past 90 days. VIEW TWEETS
27 Citations
312 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 27 extracted citations


Publications referenced by this paper.
Showing 1-10 of 312 references

The role of amylin in the control of energy homeostasis

  • TA Lutz
  • Am J Physiol Regul Integr Comp Physiol 298:R1475…
  • 2010
Highly Influential
5 Excerpts

Similar Papers

Loading similar papers…