Amygdalar participation in tonic ACTH secretion in the rat.

  title={Amygdalar participation in tonic ACTH secretion in the rat.},
  author={John Paul Allen and Catherine F. Allen},
  volume={19 2},
The role of the amygdaloid complexes in the compensatory hypersecretion of ACTH following adrenalectomy was studied in the adult male rat. Unilateral or bilateral radiofrequency or knife-cut lesions were placed in the amygdalae, their efferent pathways or the septal region. Three weeks following adrenalectomy resting plasma ACTH concentrations were measured by radioimmunoassay. Bilateral lesions of a direct medial-projecting portion of the ventral amygdalo-hypothalamic pathway blocked the… CONTINUE READING

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